New Hope to Replace Opioid Painkillers with Safer Alternative

by Karl Voigt

Researcher led by scientists from The University of Texas have revealed the results of their extensive research into a new pain medication that may provide an alternative to addictive opioids.

You may have read on this blog how researchers have focused on the sigma-1 nerve receptor protein in developing opioid pain alternatives. However, new research more than suggests that new medicine can be made from a group of molecules that bind with a sister receptor called sigma-1, little of which until recently  has been known.

Historically, and into the present, opioid medications like oxycodone and OxyContin can combat pain effectively. Unfortunately, to maintain efficacy, doctors have to increase the dosage. Further, these medications are physically addicting and can lead to reliance on non-prescription opioids.

All of us know very well of our country’s opioid crisis. The President’s Commission on Combating Drug Addiction and the Opioid Crisis has even urged President Trump to declare a federal state of emergency. Every day 142 Americans die of a drug overdose, most from heroin.

This is an entirely new class of medication that will hopefully not be addictive, and perhaps even more effective than opioids.

The downside is, of course, the drug must go through the laborious process of testing and approval. For more, read here.

One thought on “New Hope to Replace Opioid Painkillers with Safer Alternative

  1. What opioid addiction? I have taken various prescription pain meds for decades. I recently got tired of the doctor calling me in for surprise pill counts because I was never “doped” up during blood work or pee tests. Yeah, accused of hoarding or selling my pain meds. My body is severely damaged, spinal arthritis alone is enough to make me want to scream at times. However, I got tired of the bullshit inspections and told my doctor to “stuff the damn pills, I’ll do without em'”. Do I still want to scream at times? yep. I live in pain 24/7. The meds were for the bad days. Doc didn’t get that. So, now I have none. Non opioid nerve pills (muscle relaxants) do not work. So, some days I do not do well. I function about two hours plus or minus and that’s about it. Stuff your damn opioid crisis. I don’t have one. Unless you count telling the doctor to keep the damn things.


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